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Bone Substitute Biomaterials: Revolutionizing Orthopedic Surgery and Tissue Engineering

Leo Mitchell

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Published in Bone Substitute Biomaterials (Woodhead Publishing In Biomaterials 78)

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Bone defects caused by trauma, disease, or congenital malformations pose significant challenges in healthcare. Traditional treatment methods often involve bone grafting, which can lead to complications such as infection, donor site morbidity, and delayed healing. Bone substitute biomaterials offer a promising alternative by providing a matrix for bone regeneration and repair.

Bone Substitute Biomaterials (Woodhead Publishing in Biomaterials 78)

Bone Substitute Biomaterials (Woodhead Publishing Series in Biomaterials Book 78)

by Jodi Taylor

5 out of 5

Language	:	English
File size	:	7225 KB
Text-to-Speech	:	Enabled
Screen Reader	:	Supported
Enhanced typesetting	:	Enabled
Print length	:	352 pages

This comprehensive guide delves into the fascinating world of bone substitute biomaterials, exploring their role in transforming orthopedic surgery and tissue engineering. Join us as we uncover the latest advancements, materials, and applications in this burgeoning field.

Chapter 1: Understanding Bone Defects and Biomaterials

This chapter introduces the types and causes of bone defects, emphasizing the limitations of autografting and allografting. You'll gain insights into the properties and requirements of ideal bone substitute biomaterials, including biocompatibility, osteoconductivity, and mechanical strength.

Chapter 2: Materials and Fabrication of Bone Substitute Biomaterials

Discover the vast array of materials used in bone substitute biomaterials, including ceramics, polymers, metals, and composites. This chapter delves into the fabrication techniques, such as 3D printing, electrospinning, and molding, that shape these biomaterials into functional scaffolds.

Chapter 3: Bioactive and Biodegradable Bone Substitute Biomaterials

Explore the realm of bioactive bone substitute biomaterials that actively stimulate bone regeneration by releasing growth factors and ions. Biodegradable biomaterials, on the other hand, gradually dissolve over time, leaving behind newly formed bone tissue.

Chapter 4: Clinical Applications in Orthopedic Surgery

Witness the transformative applications of bone substitute biomaterials in orthopedic surgery. Learn how they enhance procedures such as spinal fusion, fracture repair, and joint replacement. Case studies and examples illustrate the practical applications and clinical outcomes.

Chapter 5: Tissue Engineering and Regenerative Medicine

Delve into the frontiers of tissue engineering, where bone substitute biomaterials serve as scaffolds for growing new bone tissue. Explore advanced technologies like induced pluripotent stem cells (iPSCs) and gene editing, which hold immense promise for regenerative medicine.

Chapter 6: Future Directions and Challenges

Peer into the future of bone substitute biomaterials. Discover emerging trends, such as personalized medicine and nano-engineered scaffolds. Analyze the challenges and opportunities in advancing this field, paving the way for even more effective orthopedic and regenerative treatments.

Bone Substitute Biomaterials: Woodhead Publishing in Biomaterials 78 is an invaluable resource for clinicians, researchers, and anyone interested in the transformative power of biomaterials in orthopedic surgery and tissue engineering. By delving into the latest advancements, materials, and applications, this book empowers you to stay at the forefront of this rapidly evolving field.

Bone Substitute Biomaterials: Revolutionizing Orthopedic Surgery And Tissue Engineering Bone Substitute Biomaterials (Woodhead Publishing In Biomaterials 78)